KGF (FGF7) (Center) Rabbit Polyclonal Antibody

CAT#: AP51660PU-N

KGF (FGF7) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

FGF7 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FGF7 antibody detected the FGF7 protein (arrow).

• 

  FGF7 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human M.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGF7 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 64-94 amino acids from the Central region of human FGF7
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 22509 Da
• Gene Name: Homo sapiens fibroblast growth factor 7 (FGF7)
• Database Link:
  Entrez Gene 2252 Human
• Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
• Synonyms: Keratinocyte growth factor, Fibroblast growth factor 7, HBGF7

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton