GAB3 (N-term) Rabbit Polyclonal Antibody

CAT#: AP51753PU-N

GAB3 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GAB3 Antibody (N-term) in human placenta tissue lysates (35ug/lane). This demonstrates the GAB3 antibody detected the GAB3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of Human GAB3
• Specificity: This antibody recognizes Human GAB3 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens GRB2 associated binding protein 3 (GAB3), transcript variant 1
• Database Link:
  Entrez Gene 139716 Human
• Background: GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: GRB2-associated-binding protein 3
• Note: Molecular Weight: 65589 Da