GALNT6 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51771PU-N

GALNT6 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GALNT6 Antibody (C-term) in Hela cell line lysates (35ug/lane). This demonstrates the GALNT6 antibody detected the GALNT6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human GALNT6
• Specificity: This antibody recognizes Human GALNT6 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens polypeptide N-acetylgalactosaminyltransferase 6 (GALNT6)
• Database Link:
  Entrez Gene 11226 Human
• Background: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
• Synonyms: GalNAc transferase 6, pp-GaNTase 6, GalNAc-T6
• Note: Molecular Weight: 71159 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, O-Glycan biosynthesis