GCNT2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51803PU-N

GCNT2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GCNT2 / NACGT1 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). This demonstrates the GCNT2 antibody detected the GCNT2 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma reacted with GCNT2 / NACGT1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of Human GCNT2 / NACGT1
• Specificity: This antibody recognizes Human and Mouse GCNT2 / NACGT1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2), transcript variant 2
• Database Link:
  Entrez Gene 2651 Human
  UniProt ID Q8N0V5
• Background: This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
• Synonyms: I-branching enzyme, IGNT, GCNT5
• Note: Molecular Weight: 45855 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways