Ghrelin Receptor (GHSR) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51836PU-N

Ghrelin Receptor (GHSR) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Ghrelin receptor / GHSR Antibody (C-term) in NCI-H292 cell line and mouse bladder tissue lysates (35ug/lane). This demonstrates the GHSR antibody detected the GHSR protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue reacted with Ghrelin receptor / GHSR Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of Human Ghrelin receptor / GHSR
• Specificity: This antibody recognizes Human and Mouse Ghrelin receptor / GHSR (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1b
• Database Link:
  Entrez Gene 208188 MouseEntrez Gene 2693 Human
• Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
• Synonyms: GH-releasing peptide receptor, GHRP
• Note: Molecular Weight: 41329 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction