GMPR1 (GMPR) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51869PU-N

GMPR1 (GMPR) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of GMPR (arrow) using GMP reductase 1 / GMPR1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GMPR gene.

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma reacted with GMP reductase 1 / GMPR1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 237-267 amino acids from the C-terminal region of human GMPR
• Specificity: This antibody recognizes Human GMP reductase 1 / GMPR1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens guanosine monophosphate reductase (GMPR)
• Database Link:
  Entrez Gene 2766 Human
• Background: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
• Synonyms: GMPR1
• Note: Molecular Weight: 37419 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism