G protein coupled receptor 30 (GPER1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51907PU-N

G protein coupled receptor 30 (GPER1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

GPER Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the GPER antibody detected the GPER protein (arrow).

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  GPER Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GPER antibody detected the GPER protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human GPER
• Specificity: This antibody reacts to GPER.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A followed by peptide affinity purification.
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 42248 Da
• Gene Name: Homo sapiens G protein-coupled estrogen receptor 1 (GPER1), transcript variant 3
• Database Link:
  Entrez Gene 76854 MouseEntrez Gene 2852 Human
• Background: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq].
• Synonyms: G-protein coupled receptor 30, Chemoattractant receptor-like 2, GPCR-BR, CEPR, CMKRL2, DRY12, FEG1, LYGPR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane