GRAP2 (Center) Rabbit Polyclonal Antibody

CAT#: AP51943PU-N

GRAP2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GRAP2 Antibody (Center) in MCF-7 cell line lysates (35ug/lane). This demonstrates the GRAP2 antibody detected the GRAP2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of Human GRAP2
• Specificity: This antibody recognizes Human GRAP2 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens GRB2-related adaptor protein 2 (GRAP2), transcript variant 3
• Database Link:
  Entrez Gene 9402 Human
• Background: This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
• Synonyms: GADS, GRBLG, GRB2L, Grf-40, GRBX, GRID
• Note: Molecular Weight: 37909 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: T cell receptor signaling pathway