Uroguanylin (GUCA2B) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51983PU-N

Uroguanylin (GUCA2B) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GUCA2B Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the GUCA2B antibody detected the GUCA2B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 68-97 amino acids from the C-terminal region of human GUCA2B
• Specificity: This antibody recognizes Human GUCA2B (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens guanylate cyclase activator 2B (GUCA2B)
• Database Link:
  Entrez Gene 2981 Human
• Background: Uroguanylin and guanylin (GUCA2A; MIM 139392), peptide homologs of the bacterial heat-stable enterotoxins (e.g., the E. coli ST toxin; STa), are endogenous activators of the guanylate cyclase-2C receptor (GUCY2C; MIM 601330), which synthesizes cyclic GMP (cGMP), a key component of several intracellular signal transduction pathways.
• Synonyms: Guanylate cyclase activator 2B, Guanylate cyclase C-activating peptide 2, GCAP-II, Uroguanylin, UGN
• Note: Molecular Weight: 12069 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane