HEPC (HAMP) (Center) Rabbit Polyclonal Antibody

CAT#: AP51998PU-N

HEPC (HAMP) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Hepcidin / HAMP Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). HAMP (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 24~54 amino acids from the Central region of Human Hepcidin / HAMP
• Specificity: This antibody recognizes Human Hepcidin / HAMP (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: hepcidin antimicrobial peptide
• Database Link:
  Entrez Gene 57817 Human
  UniProt ID P81172
• Background: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.
• Synonyms: LEAP-1, HEPC, LEAP1, PLTR
• Note: Molecular Weight: 9408 Da

Reference Data

• Protein Families: Secreted Protein, Transmembrane