HB EGF (HBEGF) (Center) Rabbit Polyclonal Antibody

CAT#: AP52008PU-N

HB EGF (HBEGF) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HBEGF Antibody (Center) in K562 cell line lysates (35ug/lane).This demonstrates the HBEGF antibody detected the HBEGF protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of Human HBEGF
• Specificity: This antibody recognizes Human HBEGF (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: heparin binding EGF like growth factor
• Database Link:
  Entrez Gene 1839 Human
  UniProt ID Q99075
• Background: HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
• Synonyms: DTR, DTS, HEGFL
• Note: Molecular Weight: 23067 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway