NEDL2 (HECW2) (Center) Rabbit Polyclonal Antibody

CAT#: AP52027PU-N

NEDL2 (HECW2) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HECW2 Antibody (Center) in mouse brain tissue lysates (35ug/lane). This demonstrates the HECW2 antibody detected the HECW2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human HECW2
• Specificity: This antibody recognizes Human and Mouse HECW2 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (HECW2), transcript variant 1
• Database Link:
  Entrez Gene 57520 Human
• Background: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
• Synonyms: HECT, HECW2, KIAA1301
• Note: Molecular Weight: 175769 Da

Reference Data

• Protein Families: Druggable Genome