PGEA1 (CBY1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52100PU-N

PGEA1 (CBY1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CBY1 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane).

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with CBY1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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  Flow cytometric analysis of MDA-MB231 cells using CBY1 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 97~126 amino acids from the C-terminal region of human CBY1
• Specificity: This antibody recognizes Human CBY1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens chibby homolog 1 (Drosophila) (CBY1), transcript variant 2
• Database Link:
  Entrez Gene 25776 Human
• Background: Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.
• Synonyms: Protein chibby homolog 1, PKD2 interactor, PIGEA-14, ARB1, C22orf2, CBY, PGEA1, HRIHFB2025, ARPP-binding protein
• Note: Molecular Weight: 14470 Da

Reference Data

• Protein Families: Transcription Factors