5HT4 Receptor (HTR4) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52130PU-N

5HT4 Receptor (HTR4) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HTR4 Antibody (N-term) in MDA-MB453 cell line and mouse liver tissue lysates (35ug/lane). This demonstrates the HTR4 antibody detected the HTR4 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human Serotonin receptor 4 (HTR4).
• Specificity: This antibody recognizes Human Serotonin receptor 4 (HTR4) (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens 5-hydroxytryptamine receptor 4 (HTR4), transcript variant b
• Database Link:
  Entrez Gene 3360 Human
• Background: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.
• Synonyms: 5-hydroxytryptamine receptor 4, 5-HT4, 5-HT-4
• Note: Molecular Weight: 43761 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction