IGF2BP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52165PU-N

IGF2BP1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

IGF2BP1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IGF2BP1 antibody detected the IGF2BP1 protein (arrow).

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  IGF2BP1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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  IGF2BP1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 515-542 amino acids from the C-terminal region of human IGF2BP1
• Specificity: This antibody reacts to IGF2BP1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 63481 Da
• Gene Name: insulin like growth factor 2 mRNA binding protein 1
• Database Link:
  Entrez Gene 10642 Human
  UniProt ID Q9NZI8
• Background: IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CRDBP, VICKZ1, ZBP1, CRD-BP, ZBP-1