IGF2BP2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52166PU-N

IGF2BP2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

IGF2BP2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IGF2BP2 antibody detected the IGF2BP2 protein (arrow).

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  IGF2BP2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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  IGF2BP2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 537-564 amino acids from the C-terminal region of human IGF2BP2
• Specificity: This antibody reacts to IGF2BP2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 66121 Da
• Gene Name: Homo sapiens insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2), transcript variant 2
• Database Link:
  Entrez Gene 10644 Human
• Background: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Synonyms: IMP2, IMP-2, VICKZ2