INSC (Center) Rabbit Polyclonal Antibody

CAT#: AP52216PU-N

INSC (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of INSC Antibody (Center) in WiDr cell line lysates (35ug/lane). INSC (arrow) was detected using the purified Pab.

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded hepatocarcinoma reacted with INSC Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 416~446 amino acids from the Central region of Human INSC
• Specificity: This antibody recognizes Human INSC (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens inscuteable homolog (Drosophila) (INSC), transcript variant 1
• Database Link:
  Entrez Gene 387755 Human
• Background: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).
• Synonyms: Protein inscuteable homolog
• Note: Molecular Weight: 63469 Da