IP3KC (ITPKC) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52258PU-N

IP3KC (ITPKC) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of ITPKC Antibody (N-term) in HepG2 cell line lysates (35ug/lane). ITPKC (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ITPKC Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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  Flow cytometric analysis of CEM cells using ITPKC Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution:

  Peptide ELISA: 1/1000.
  Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human ITPKC.
• Specificity: This antibody recognizes Human IP3 3-kinase C / ITPKC (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC)
• Database Link:
  Entrez Gene 80271 Human
• Background: ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.
• Synonyms: IP3KC, InsP3-kinase C, IP3K-C
• Note: Molecular Weight: 75207 Da

Reference Data

• Protein Families: Druggable Genome