KDM5A (C-term) Rabbit Polyclonal Antibody

CAT#: AP52263PU-N

KDM5A (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of JARID1A Antibody (C-term) in UM cell line lysates (35ug/lane). This demonstrates the JARID1A antibody detected the JARID1A protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with JARID1A Antibody (C-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1608-1641 amino acids from the C-terminal region of Human JARID1A
• Specificity: This antibody recognizes Human JARID1A (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens lysine (K)-specific demethylase 5A (KDM5A), transcript variant 2
• Database Link:
  Entrez Gene 5927 Human
  UniProt ID P29375
• Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.
• Synonyms: KDM5A
• Note: Molecular Weight: 186;838 Da

Reference Data

• Protein Families: Druggable Genome