Kv4.2 (KCND2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52303PU-N

Kv4.2 (KCND2) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KCND2 Antibody (N-term) in K562 cell line lysates (35ug/lane).This demonstrates the KCND2 antibody detected the KCND2 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with KCND2 Antibody (N-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 122-151 amino acids from the N-terminal region of human KCND2
• Specificity: This antibody recognizes Human KCND2 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens potassium voltage-gated channel subfamily D member 2 (KCND2)
• Database Link:
  Entrez Gene 3751 Human
• Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
• Synonyms: Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2, KIAA1044
• Note: Molecular Weight: 70537 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane