KCNH4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP52304PU-N

KCNH4 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KCNH4 Antibody (N-term) in K562 cell line lysates (35ug/lane). This demonstrates the KCNH4 antibody detected the KCNH4 protein (arrow).

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  Flow cytometric analysis of K562 cells using KCNH4 Antibody (N-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human KCNH4
• Specificity: This antibody recognizes Human KCNH4 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens potassium voltage-gated channel subfamily H member 4 (KCNH4)
• Database Link:
  Entrez Gene 23415 Human
• Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.
• Synonyms: KCNH4, ELK channel 1, ELK1, Brain-specific eag-like channel 2, BEC2
• Note: Molecular Weight: 111693 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane