KCNQ3 (C-term) Rabbit Polyclonal Antibody
Other products for "KCNQ3"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 650-679 amino acids from the C-terminal region of human KCNQ3 |
Specificity | This antibody recognizes Human and Mouse KCNQ3 (C-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 2 |
Database Link | |
Background | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). |
Synonyms | Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3, Potassium channel subunit alpha KvLQT3, KQT-like 3 |
Note | Molecular Weight: 96742 Da |
Reference Data | |
Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
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