KCNQ3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52317PU-N

KCNQ3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KCNQ3 Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). This demonstrates the KCNQ3 antibody detected the KCNQ3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 650-679 amino acids from the C-terminal region of human KCNQ3
• Specificity: This antibody recognizes Human and Mouse KCNQ3 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 2
• Database Link:
  Entrez Gene 110862 MouseEntrez Gene 3786 Human
• Background:
  The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).
• Synonyms: Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3, Potassium channel subunit alpha KvLQT3, KQT-like 3
• Note: Molecular Weight: 96742 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane