Kinesin 5C (KIF5C) Rabbit Polyclonal Antibody

CAT#: AP52366PU-N

Kinesin 5C (KIF5C) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in Mouse brain tissue lysates (35ug/lane) using Kif5C-2 Antibody. This demonstrates the Kif5C-2 antibody detected the Kif5C-2 protein (arrow).

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  Formalin Fixed, Paraffin Embedded Human brain tissue stained with Kif5C-2 Antibody followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of Kif5C-2 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from Human KIF5C
• Specificity: This antibody is specific for Kif5C-2
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 109495 Da
• Gene Name: Homo sapiens kinesin family member 5C (KIF5C), transcript variant 1
• Database Link:
  Entrez Gene 16574 MouseEntrez Gene 3800 Human
• Background: Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain.There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.
• Synonyms: KIF5C, KIAA0531, NKHC2, Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2

Reference Data

• Protein Families: Druggable Genome