KREMEN2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52408PU-N

KREMEN2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

KREMEN2 Antibody (Center) western blot analysis in ZR-75-1, K562, NCI-H460 cell line lysates (35ug/lane).This demonstrates the KREMEN2 antibody detected the KREMEN2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2
• Specificity: This antibody reacts to KREMEN2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2
• Database Link:
  Entrez Gene 79412 Human
• Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
• Synonyms: KREMEN2, KRM2, Dickkopf receptor 2
• Note: Molecular Weight: 48849 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane