Galectin 3 (LGALS3) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52468PU-N

Galectin 3 (LGALS3) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Galectin-3 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow).

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  Flow cytometric analysis of MCF-7 cells usinmg Galectin-3 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human Galectin-3
• Specificity: This antibody recognizes Human Galectin-3 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens galectin 3 (LGALS3), transcript variant 1
• Database Link:
  Entrez Gene 3958 Human
• Background: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
• Synonyms: Mac-2, Lgals3, GAL3, GALBP, CBP35, L-31
• Note: Molecular Weight: 26152 Da

Reference Data

• Protein Families: Secreted Protein