LOXL2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52514PU-N

LOXL2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of LOXL2 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the LOXL2 antibody detected the LOXL2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of Human LOXL2
• Specificity:
  This antibody recognizes Human LOXL2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens lysyl oxidase like 2 (LOXL2)
• Database Link:
  Entrez Gene 4017 Human
• Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
• Synonyms: Lysyl oxidase homolog 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14
• Note: Molecular Weight: 86725 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein