LRP5 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52526PU-N

LRP5 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of LRP5 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). This demonstrates the LRP5 antibody detected the LRP5 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1162-1190 amino acids from the C-terminal region of Human LRP5
• Specificity: This antibody recognizes Human and Mouse LRP5 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens LDL receptor related protein 5 (LRP5), transcript variant 1
• Database Link:
  Entrez Gene 16973 MouseEntrez Gene 4041 Human
• Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
• Synonyms: LRP7, LRP-5
• Note: Molecular Weight: 179145 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Wnt signaling pathway