LTBR (N-term) Rabbit Polyclonal Antibody

CAT#: AP52559PU-N

LTBR (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of LTBR Antibody (N-term) in mouse brain tissue lysates (35ug/lane). This demonstrates the LTBR antibody detected the LTBR protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human LTBR
• Specificity: This antibody recognizes Human and Mouse LTBR (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens lymphotoxin beta receptor (LTBR), transcript variant 1
• Database Link:
  Entrez Gene 17000 MouseEntrez Gene 4055 Human
• Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
• Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR, TNFRSF3, D12S370, Lymphotoxin-beta receptor
• Note: Molecular Weight: 46709 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction