ARMET (MANF) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52596PU-N

ARMET (MANF) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of ARMET / ARP Antibody (N-term) in 293 cell line lysates (35ug/lane). This demonstrates the MANF antibody detected the MANF protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human ARMET / ARP
• Specificity: This antibody recognizes Human ARMET / ARP (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens mesencephalic astrocyte derived neurotrophic factor (MANF)
• Database Link:
  Entrez Gene 7873 Human
• Background: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
• Synonyms: Arginine-rich protein, MANF
• Note: Molecular Weight: 20257 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein