ME2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52647PU-N

ME2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of NAD-ME Antibody (C-term) in mouse NIH-3T3, Neuro-2a cell line lysates (35ug/lane).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue reacted with NAD-ME Antibody (C-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of Human NAD-ME
• Specificity: This antibody recognizes Human and Mouse NAD-ME (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2), transcript variant 1
• Database Link:
  Entrez Gene 107029 MouseEntrez Gene 4200 Human
• Background:
  This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq].
• Synonyms: ME2
• Note: Molecular Weight: 65444 Da

Reference Data

• Protein Pathways: Pyruvate metabolism