CRSP9 (MED7) (Center) Rabbit Polyclonal Antibody
Other products for "MED7"
Specifications
Product Data | |
Applications | FC, WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human MED7 |
Specificity | This antibody recognizes Human MED7 (Center). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens mediator complex subunit 7 (MED7), transcript variant 1 |
Database Link | |
Background | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]. |
Synonyms | ARC34, CRSP9, Mediator complex subunit 7 |
Note | Molecular Weight: 27245 Da |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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