MSX2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52762PU-N

MSX2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MSX2 Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the MSX2 antibody detected the MSX2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human MSX2
• Specificity: This antibody recognizes Human MSX2 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens msh homeobox 2 (MSX2)
• Database Link:
  Entrez Gene 4488 Human
• Background:
  This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
• Synonyms: MSX-2, HOX8, HOX-8
• Note: Molecular Weight: 28897 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors