NEIL1 (Center) Rabbit Polyclonal Antibody

CAT#: AP52849PU-N

NEIL1 (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of NEIL1 Antibody (Center) in A2058 cell line lysates (35ug/lane). NEIL1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 137~167 amino acids from the Central region of human NEIL1
• Specificity: This antibody recognizes Human NEIL1 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens nei like DNA glycosylase 1 (NEIL1), transcript variant 2
• Database Link:
  Entrez Gene 79661 Human
• Background: NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).
• Synonyms: NEH1, FPG1
• Note: Molecular Weight: 43684 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair