Parp2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53164PU-N

Parp2 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of PARP2 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). This demonstrates the PARP2 antibody detected the PARP2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 313-344 amino acids from the C-terminal region of Human PARP2
• Specificity: This antibody recognizes Human and Mouse PARP2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Mus musculus poly (ADP-ribose) polymerase family, member 2 (Parp2)
• Database Link:
  Entrez Gene 10038 HumanEntrez Gene 11546 Mouse
• Background: Parp2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
• Synonyms: PARP-2, ADPRT2, ADPRTL2, Poly [ADP-ribose] polymerase 2, PARP 2, EC=2.4.2.30, pADPRT-2
• Note: Molecular Weight: 63397 Da