PAX7 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53182PU-N

PAX7 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

PAX7 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the PAX7 antibody detected the PAX7 protein (arrow).

• 

  PAX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human PAX7
• Specificity: This antibody reacts to PAX7.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 56896 Da
• Gene Name: Homo sapiens paired box 7 (PAX7), transcript variant 3
• Database Link:
  Entrez Gene 18509 MouseEntrez Gene 5081 Human
• Background: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Pax-7, HUP1

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors