PD L2 (PDCD1LG2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP53228PU-N

PD L2 (PDCD1LG2) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD273 / PDL2 Antibody (N-term) in ZR-75-1 cell line lysates (35ug/lane).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue reacted with CD273 / PDL2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 45-75 amino acids from the N-terminal region of Human CD273 / PDL2
• Specificity:
  This antibody recognizes Human CD273 / PDL2 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens programmed cell death 1 ligand 2 (PDCD1LG2)
• Database Link:
  Entrez Gene 80380 Human
• Background: PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
• Synonyms: PD-L2, PD-1-ligand 2, PDCD1 ligand 2, PDCD1LG2, B7DC, PDCD1L2
• Note: Molecular Weight: 30957 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)