PDE7B (C-term) Rabbit Polyclonal Antibody

CAT#: AP53239PU-N

PDE7B (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PDE7B Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the PDE7B antibody detected the PDE7B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 424-454 amino acids from the C-terminal region of Human PDE7B
• Specificity: This antibody recognizes Human PDE7B (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens phosphodiesterase 7B (PDE7B)
• Database Link:
  Entrez Gene 27115 Human
• Background: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
• Synonyms: Phosphodiesterase 7B, MGC88256
• Note: Molecular Weight: 51835 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Progesterone-mediated oocyte maturation, Purine metabolism