PGAM2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP53269PU-N

PGAM2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PGAM2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow).

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  Western blot analysis of PGAM2 Antibody (N-term) in mouse testis tissue lysates (35ug/lane). This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle reacted with PGAM2 Antibody (N-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of the PGAM2 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human PGAM2
• Specificity: This antibody recognizes Human and Mouse PGAM2 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens phosphoglycerate mutase 2 (PGAM2)
• Database Link:
  Entrez Gene 56012 MouseEntrez Gene 5224 Human
• Background: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.
• Synonyms: PGAM 2, Phosphoglycerate mutase 2, PGAMM, PGAM-M
• Note: Molecular Weight: 28766 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycolysis / Gluconeogenesis, Metabolic pathways