PIK3AP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53304PU-N

PIK3AP1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in A549 cell line lysates (35ug/lane) using PIK3AP1 antibody. (C-term). This demonstrates the PIK3AP1 antibody detected the PIK3AP1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 646-676aa) of human PIK3AP1.
• Specificity: This antibody recognizes PIK3AP1 at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1)
• Database Link:
  Entrez Gene 118788 Human
• Background: PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. It couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. PIK3AP1 seems to have a complementary role with CD19 in PI3K activation (By similarity) and is may be involved in the survival of mature B cells via activation of REL (By similarity).
• Synonyms: BCAP
• Note: Molecular Weight: 70kd Isoform 2. 90398 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway