Plakophilin 2 (PKP2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53319PU-N

Plakophilin 2 (PKP2) (C-term) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1000. 
Western  lot: 1/100-1/500. 
Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 837-866 amino acids from the C-terminal region of Human Plakophilin-2
Specificity This antibody recognizes Human  Plakophilin-2 (C-term).
Formulation PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens plakophilin 2 (PKP2), transcript variant 2b
Background This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
Synonyms PKP2
Note Molecular Weight: 97415 Da
Reference Data
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.