PLOD3 (N-term) Rabbit Polyclonal Antibody

CAT#: AP53355PU-N

PLOD3 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PLOD3 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the PLOD3 antibody detected the PLOD3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 85-113 amino acids from the N-terminal region of human PLOD3
• Specificity: This antibody recognizes Human PLOD3 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3)
• Database Link:
  Entrez Gene 8985 Human
• Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
• Synonyms: Lysyl hydroxylase 3
• Note: Molecular Weight: 84785 Da

Reference Data

• Protein Pathways: Lysine degradation