POLD3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53378PU-N

POLD3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of POLD3 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the POLD3 antibody detected the POLD3 protein (arrow).

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  Western blot analysis of POLD3 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). This demonstrates the POLD3 antibody detected the POLD3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human POLD3
• Specificity: This antibody recognizes Human and Mouse POLD3 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinitty Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens polymerase (DNA-directed), delta 3, accessory subunit (POLD3), transcript variant 1
• Database Link:
  Entrez Gene 67967 MouseEntrez Gene 10714 Human
• Background: The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2 (MIM 600815), POLD3, and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]). [supplied by OMIM].
• Synonyms: DNA polymerase delta subunit 3, KIAA0039
• Note: Molecular Weight: 51400 Da

Reference Data

• Protein Pathways: Base excision repair, DNA replication, Homologous recombination, Metabolic pathways, Mismatch repair, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism