PREX1 (Center) Rabbit Polyclonal Antibody

CAT#: AP53440PU-N

PREX1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PREX1 Antibody (Center) in MCF-7 cell line lysates (35ug/lane). PREX1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 573~602 amino acids from the Central region of human PREX1
• Specificity: This antibody reacts to PREX1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 186203 Da
• Gene Name: Homo sapiens phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1)
• Database Link:
  Entrez Gene 57580 Human
• Background: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
• Synonyms: P-Rex1, KIAA1415

Reference Data

• Protein Pathways: Chemokine signaling pathway