Trypsin (PRSS3) (Center) Rabbit Polyclonal Antibody

CAT#: AP53469PU-N

Trypsin (PRSS3) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PRSS3 Antibody (Center) in HL-60, MDA-MB231 cell line lysates (35ug/lane). This demonstrates the PRSS3 antibody detected the PRSS3 protein (arrow).

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  Formalin fixed and paraffin embedded human pancreas tissue reacted with RSS3 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining.

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  Flow cytometric analysis of HL-60 cells using RSS3 Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 143-171 amino acids from the Central region of Human Trypsin-3 / PRSS3
• Specificity: This antibody recognizes Human Trypsin-3 / PRSS3 (Center).
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens T cell receptor beta variable orphans on chromosome 9 (TRBVOR9@) on chromosome 9
• Database Link:
  Entrez Gene 5646 Human
• Background: This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
• Synonyms: PRSS4, TRY3, TRY4, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV
• Note: Molecular Weight: 32529 Da

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Neuroactive ligand-receptor interaction