PSTPIP1 (N-term) Rabbit Polyclonal Antibody
Other products for "PSTPIP1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1 |
Specificity | This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term). |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), transcript variant 1 |
Database Link | |
Background | The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. |
Synonyms | PSTPIP, H-PIP, PAPAS, CD2BP1L, CD2BP1S, CD2-binding protein 1 |
Note | Molecular Weight: 47591 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | NOD-like receptor signaling pathway |
Documents
Product Manuals |
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