PTPD2 (PTPN14) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53509PU-N

PTPD2 (PTPN14) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in mouse bladder tissue lysates (35ug/lane) using PTPN14 / PEZ antibody. (C-term). This demonstrates the PTPN14 antibody detected the PTPN14 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 861-890aa) of human PTPN14 / PEZ (C-term)
• Specificity: This antibody recognizes PTPN14 / PEZ at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens protein tyrosine phosphatase, non-receptor type 14 (PTPN14)
• Database Link:
  Entrez Gene 5784 Human
• Background: The protein encoded by the PTPN14 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
• Synonyms: PTP36, PTPD2
• Note: Molecular Weight: 135261 Da

Reference Data

• Protein Families: Druggable Genome