PTPRD (N-term) Rabbit Polyclonal Antibody

CAT#: AP53514PU-N

PTPRD (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PTPRD (arrow) in Hela cell line lysates (35ug/lane) using PTPRD antibody. (N-term).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 350-379aa) of human PTPRD.
• Specificity: This antibody recognizes PTPRD at N-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens protein tyrosine phosphatase, receptor type D (PTPRD), transcript variant 1
• Database Link:
  Entrez Gene 5789 Human
• Background: PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
• Synonyms: R-PTP-delta, Protein-tyrosine phosphatase delta
• Note: Molecular Weight: 214760 Da

Reference Data

• Protein Families: Druggable Genome, Phosphatase, Transmembrane