RASAL1 (Center) Rabbit Polyclonal Antibody

CAT#: AP53584PU-N

RASAL1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of RASAL1 Antibody in Mouse liver tissue lysates (35ug/lane). This demonstrates the RASAL1 antibody detected the RASAL1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 308-337 amino acids from the Central region of Human RASAL1.
• Specificity: This antibody recognizes Mouse RASAL1 (Center).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens RAS protein activator like 1 (GAP1 like) (RASAL1), transcript variant 3
• Database Link:
  Entrez Gene 8437 Human
• Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
• Synonyms: RASAL-1, RASAL, RasGAP-activating-like protein 1
• Note: Molecular Weight: 90016 Da