RUSC2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP53771PU-N

RUSC2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in Human Placenta tissue lysates (35 ug/lane) using RUSC2 Antibody (N-term). This demonstrates the RUSC2 antibody detected the RUSC2 protein (arrow).

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  Immunohistochemistry analysis in Formalin Fixed, Paraffin embedded Human brain tissue stained with RUSC2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of RUSC2 Antibody (N-term) for Immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 315-344 amino acids from the N-terminal region of Human RUSC2
• Specificity: Recognizes RUSC2 (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens RUN and SH3 domain containing 2 (RUSC2), transcript variant 1
• Database Link:
  Entrez Gene 9853 Human
• Background: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
• Synonyms: KIAA0375, Interacting protein of Rab1
• Note: Molecular Weight: 161195 Da