S100A1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53776PU-N

S100A1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in MDA-MB435 cell line lysates (35 ug/lane) using S100A1 Antibody (Center). This demonstrates the S100A1 antibody detected the S100A1 protein (arrow).

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  Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue using S100A1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of S100A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 52-83 amino acids from the C-terminal region of Human S100A1
• Specificity: Recognizes S100A1 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens S100 calcium binding protein A1 (S100A1)
• Database Link:
  Entrez Gene 6271 Human
• Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
• Synonyms: S100-A1, S100A, S100 alpha, S100 calcium-binding protein A1, S-100 protein subunit alpha, S-100 protein alpha chain
• Note: Molecular Weight: 10546 Da